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Vascular Morphogenesis and Remodeling in a Human Tumor Xenograft: Blood Vessel Formation and Growth After Ovariectomy and Tumor Implantation

To determine mechanisms of blood vessel formation and growth in solid tumors, we used a model in which LS174T human colon adenocarcinomas are grown in the isolated ovarian pedicle of nude mice. Reconstruction of 3500 histological serial sections demonstrated that a new vascular network composed of v...

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Autori principali: Patan, Sybill, Tanda, Shigeru, Roberge, Sylvie, Jones, Rosemary C., Jain, Rakesh K., Munn, Lance L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2001
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2752899/
https://ncbi.nlm.nih.gov/pubmed/11597997
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