Stem Cell Therapy with Overexpressed VEGF and PDGF Genes Improves Cardiac Function in a Rat Infarct Model

BACKGROUND: Therapeutic potential was evaluated in a rat model of myocardial infarction using nanofiber-expanded human cord blood derived hematopoietic stem cells (CD133+/CD34+) genetically modified with VEGF plus PDGF genes (VIP). METHODS AND FINDINGS: Myocardial function was monitored every two we...

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Главные авторы: Das, Hiranmoy, George, Jon C., Joseph, Matthew, Das, Manjusri, Abdulhameed, Nasreen, Blitz, Anna, Khan, Mahmood, Sakthivel, Ramasamy, Mao, Hai-Quan, Hoit, Brian D., Kuppusamy, Periannan, Pompili, Vincent J.
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2009
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Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2752797/
https://ncbi.nlm.nih.gov/pubmed/19809493
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0007325
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