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Dicer is required for female reproductive tract development and fertility in the mouse

Dicer encodes a riboendonuclease required for microRNA biosynthesis. Dicer was inactivated in Müllerian duct mesenchyme-derived tissues of the reproductive tract of the mouse, using an Amhr2-Cre allele. Although Amhr2-Cre; Dicer conditional mutant males appeared normal and were fertile, mutant femal...

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Bibliografske podrobnosti
Main Authors: Gonzalez, Gabriel, Behringer, Richard R.
Format: Artigo
Jezik:Inglês
Izdano: 2009
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2752678/
https://ncbi.nlm.nih.gov/pubmed/19197916
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mrd.21010
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