Conditional linkage and genome-wide association studies identify UGT1A1 as a major gene for anti-atherogenic serum bilirubin levels – The Framingham Heart Study

OBJECTIVE AND METHODS: Low bilirubin levels are significantly associated with cardiovascular diseases (CVD). In previous genome-wide linkage studies we identified a major locus on chromosome 2q harboring the candidate gene UDP-glucuronosyltransferase (UGT1A1). The activity of this enzyme is signific...

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Main Authors: Lin, Jing-Ping, Schwaiger, Johannes P., Cupples, L. Adrienne, O’Donnell, Christopher J., Zheng, Gang, Schoenborn, Veit, Hunt, Steven C., Joo, Jungnam, Kronenberg, Florian
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2752659/
https://ncbi.nlm.nih.gov/pubmed/19389676
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.atherosclerosis.2009.02.039
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