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Real-time imaging of histone H4 hyperacetylation in living cells

To visualize histone acetylation in living cells, we developed a genetically encoded fluorescent resonance energy transfer (FRET)-based indicator. Response of the indicator reflects changes in the acetylation state of both K5 and K8 in histone H4. Using this acetylation indicator, we were able to mo...

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Detalhes bibliográficos
Main Authors: Sasaki, Kazuki, Ito, Tamaki, Nishino, Norikazu, Khochbin, Saadi, Yoshida, Minoru
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2752582/
https://ncbi.nlm.nih.gov/pubmed/19805290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0902150106
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