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Real-time imaging of histone H4 hyperacetylation in living cells
To visualize histone acetylation in living cells, we developed a genetically encoded fluorescent resonance energy transfer (FRET)-based indicator. Response of the indicator reflects changes in the acetylation state of both K5 and K8 in histone H4. Using this acetylation indicator, we were able to mo...
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Main Authors: | , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
National Academy of Sciences
2009
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2752582/ https://ncbi.nlm.nih.gov/pubmed/19805290 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0902150106 |
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