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Positron emission tomography imaging of drug-induced tumor apoptosis with a caspase-3/7 specific [(18)F]-labeled isatin sulfonamide
Of the molecular biochemical alterations that occur during apoptosis, activation of caspases, notably caspase-3, is probably the most attractive for developing specific in vivo molecular imaging probes. We recently designed a library of isatin-5 sulfonamides and selected [(18)F]ICMT-11 for further e...
में बचाया:
| मुख्य लेखकों: | , , , , , |
|---|---|
| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
National Academy of Sciences
2009
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2752565/ https://ncbi.nlm.nih.gov/pubmed/19805307 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0901310106 |
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