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Explaining worldwide patterns of human genetic variation using a coalescent-based serial founder model of migration outward from Africa
Studies of worldwide human variation have discovered three trends in summary statistics as a function of increasing geographic distance from East Africa: a decrease in heterozygosity, an increase in linkage disequilibrium (LD), and a decrease in the slope of the ancestral allele frequency spectrum....
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
National Academy of Sciences
2009
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2752555/ https://ncbi.nlm.nih.gov/pubmed/19706453 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0903341106 |
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