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NO formation by a catalytically self-sufficient bacterial nitric oxide synthase from Sorangium cellulosum
The role of nitric oxide (NO) in the host response to infection and in cellular signaling is well established. Enzymatic synthesis of NO is catalyzed by the nitric oxide synthases (NOSs), which convert Arg into NO and citrulline using co-substrates O(2) and NADPH. Mammalian NOS contains a flavin red...
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| Главные авторы: | , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
National Academy of Sciences
2009
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2752531/ https://ncbi.nlm.nih.gov/pubmed/19805284 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0908443106 |
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