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NO formation by a catalytically self-sufficient bacterial nitric oxide synthase from Sorangium cellulosum

The role of nitric oxide (NO) in the host response to infection and in cellular signaling is well established. Enzymatic synthesis of NO is catalyzed by the nitric oxide synthases (NOSs), which convert Arg into NO and citrulline using co-substrates O(2) and NADPH. Mammalian NOS contains a flavin red...

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Main Authors: Agapie, Theodor, Suseno, Sandy, Woodward, Joshua J., Stoll, Stefan, Britt, R. David, Marletta, Michael A.
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2009
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2752531/
https://ncbi.nlm.nih.gov/pubmed/19805284
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0908443106
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