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NO formation by a catalytically self-sufficient bacterial nitric oxide synthase from Sorangium cellulosum

The role of nitric oxide (NO) in the host response to infection and in cellular signaling is well established. Enzymatic synthesis of NO is catalyzed by the nitric oxide synthases (NOSs), which convert Arg into NO and citrulline using co-substrates O(2) and NADPH. Mammalian NOS contains a flavin red...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Agapie, Theodor, Suseno, Sandy, Woodward, Joshua J., Stoll, Stefan, Britt, R. David, Marletta, Michael A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2752531/
https://ncbi.nlm.nih.gov/pubmed/19805284
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0908443106
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