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Ribosomal protein mRNAs are primary targets of regulation in RNase-L-induced senescence
The endoribonuclease RNase-L requires 2′,5′-linked oligoadenylates for activation, and mediates antiviral and antiproliferative activities. We previously determined that RNase-L activation induces senescence; to determine potential mechanisms underlying this activity, we used microarrays to identify...
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| Autori principali: | , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2009
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2752476/ https://ncbi.nlm.nih.gov/pubmed/19411840 |
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