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Guiding Conformation Space Search with an All-Atom Energy Potential

The most significant impediment for protein structure prediction is the inadequacy of conformation space search. Conformation space is too large and the energy landscape too rugged for existing search methods to consistently find near-optimal minima. To alleviate this problem, we present model-based...

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Autori principali: Brunette, TJ, Brock, Oliver
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2752431/
https://ncbi.nlm.nih.gov/pubmed/18536015
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prot.22123
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