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Eukaryotic Initiation Factor 4a3 is a Selenium-regulated RNA-binding Protein that Selectively Inhibits Selenocysteine Incorporation

The synthesis of selenoproteins requires the translational recoding of the UGA stop codon as selenocysteine. During selenium deficiency, there is a hierarchy of selenoprotein expression, with certain selenoproteins synthesized at the expense of others. The mechanism by which the limiting selenocyste...

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Detalhes bibliográficos
Main Authors: Budiman, Michael E., Bubenik, Jodi L., Miniard, Angela C., Middleton, Lisa M., Gerber, Carri A., Cash, Ayla, Driscoll, Donna M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2752292/
https://ncbi.nlm.nih.gov/pubmed/19716792
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2009.06.026
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