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A new animal model of post-surgical bowel inflammation and fibrosis: the effect of commensal microflora

OBJECTIVE: Ileo-cecal resection (ICR) is common in Crohn’s disease (CD). Inflammation and fibrosis frequently recur at the site of anastomosis or in the small intestine (SI). No animal models of post-surgical inflammation and fibrosis exist. We developed a model of ICR in IL-10 null and wild-type (W...

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Main Authors: Rigby, Rachael J., Hunt, Meagan R., Scull, Brooks P., Simmons, James G., Speck, Karen E., Helmrath, Michael A., Lund, P. Kay
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2752281/
https://ncbi.nlm.nih.gov/pubmed/19398439
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gut.2008.157636
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