Large-Scale Multiplexed Quantitative Discovery Proteomics Enabled by the Use of an (18)O-Labeled “Universal” Reference Sample

The quantitative comparison of protein abundances across a large number of biological or patient samples represents an important proteomics challenge that needs to be addressed for proteomics discovery applications. Herein, we describe a strategy that incorporates a stable isotope (18)O-labeled ″uni...

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Auteurs principaux: Qian, Wei-Jun, Liu, Tao, Petyuk, Vladislav A., Gritsenko, Marina A., Petritis, Brianne O., Polpitiya, Ashoka D., Kaushal, Amit, Xiao, Wenzhong, Finnerty, Celeste C., Jeschke, Marc G., Jaitly, Navdeep, Monroe, Matthew E., Moore, Ronald J., Moldawer, Lyle L., Davis, Ronald W., Tompkins, Ronald G., Herndon, David N., Camp, David G., Smith, Richard D.
Format: Artigo
Langue:Inglês
Publié: 2009
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2752204/
https://ncbi.nlm.nih.gov/pubmed/19053531
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/pr800467r
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