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On assessing surrogacy in a single trial setting using a semi-competing risks paradigm

There has been a recent emphasis on the identification of biomarkers and other biologic measures that may be potentially used as surrogate endpoints in clinical trials. We focus on the setting of data from a single clinical trial. In this paper, we consider a framework in which the surrogate must oc...

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Autor principal: Ghosh, Debashis
Formato: Artigo
Lenguaje:Inglês
Publicado: 2009
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2752047/
https://ncbi.nlm.nih.gov/pubmed/18759839
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1541-0420.2008.01109.x
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