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Nkx Genes Regulate Heart Tube Extension and Exert Differential Effects on Ventricular and Atrial Cell Number

Heart formation is a complex morphogenetic process, and perturbations in cardiac morphogenesis lead to congenital heart disease. NKX2-5 is a key causative gene associated with cardiac birth defects, presumably because of its essential roles during the early steps of cardiogenesis. Previous studies i...

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Autori principali: Targoff, Kimara L., Schell, Thomas, Yelon, Deborah
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2752039/
https://ncbi.nlm.nih.gov/pubmed/18718462
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2008.07.037
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