Human NKT cells promote monocyte differentiation into suppressive myeloid antigen-presenting cells

NKT cells have been shown to promote peripheral tolerance in a number of model systems, yet the processes by which they exert their regulatory effects remain poorly understood. Here, we show that soluble factors secreted by human NKT cells instruct human peripheral blood monocytes to differentiate i...

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Библиографические подробности
Главные авторы: Hegde, Subramanya, Jankowska-Gan, Ewa, Roenneburg, Drew A., Torrealba, Jose, Burlingham, William J., Gumperz, Jenny E.
Формат: Artigo
Язык:Inglês
Опубликовано: The Society for Leukocyte Biology 2009
Предметы:
Spotlight on Leading Edge Research
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2752012/
https://ncbi.nlm.nih.gov/pubmed/19465641
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.0209059
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