Simvastatin Treatment Ameliorates Autoimmune Disease Associated with Accelerated Atherosclerosis in a Murine Lupus Model

Patients with systemic lupus erythematosus develop accelerated atherosclerosis independent of traditional risk factors. The 3-hydroxy-3-methyl-glutaryl coenzyme A (HMG-CoA) reductase inhibitors are widely prescribed for hyperlipidemia, but they also exhibit anti-inflammatory actions that appear to b...

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Hauptverfasser: Aprahamian, Tamar, Bonegio, Ramon, Rizzo, Jennifer, Perlman, Harris, Lefer, David J., Rifkin, Ian R., Walsh, Kenneth
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2006
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2752011/
https://ncbi.nlm.nih.gov/pubmed/16920939
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