MicroRNAs miR-143 and miR-145 modulate cytoskeletal dynamics and responsiveness of smooth muscle cells to injury

Vascular injury triggers dedifferentiation and cytoskeletal remodeling of smooth muscle cells (SMCs), culminating in vessel occlusion. Serum response factor (SRF) and its coactivator, myocardin, play a central role in the control of smooth muscle phenotypes by regulating the expression of cytoskelet...

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Autors principals: Xin, Mei, Small, Eric M., Sutherland, Lillian B., Qi, Xiaoxia, McAnally, John, Plato, Craig F., Richardson, James A., Bassel-Duby, Rhonda, Olson, Eric N.
Format: Artigo
Idioma:Inglês
Publicat: Cold Spring Harbor Laboratory Press 2009
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2751981/
https://ncbi.nlm.nih.gov/pubmed/19720868
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1842409
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