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Antitumor bioactivity of adenovirus-mediated p27mt in colorectal cancer cell line SW480

AIM: To explore the antitumor bioactivity of adenovirus-mediated mutant type p27(kip1) gene in a colorectal cancer cell line SW480. METHODS: We constructed recombinant adenovirus vector expressing a mutant type p27(kip1) gene (ad-p27mt), with mutation of Thr-187/Pro-188 (ACGCCC) to Met-187/Ile-188 (...

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Detalhes bibliográficos
Main Authors: Sun, Ze-Qun, Deng, Chang-Sheng, Xu, Shao-Yong, Du, Yong
Formato: Artigo
Idioma:Inglês
Publicado em: The WJG Press and Baishideng 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2751892/
https://ncbi.nlm.nih.gov/pubmed/18855981
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.14.5827
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