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Thymic self-reactivity selects natural interleukin 17-producing T cells that can regulate peripheral inflammation
Interleukin 17 (IL-17)-producing CD4(+) T (T(H)-17) cells share a developmental relationship with FoxP3(+) regulatory T (T(reg)) cells. Here we show that a T(H)-17 population differentiates within the thymus in a manner influenced by self-antigen recognition, and by the cytokines IL-6 and transformi...
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| Главные авторы: | , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2009
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2751862/ https://ncbi.nlm.nih.gov/pubmed/19734905 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.1783 |
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