Two adjacent nuclear factor-binding domains activate expression from the human PRNP promoter

BACKGROUND: The transmissible spongiform encephalopathies (TSEs) comprise a group of fatal degenerative neurological diseases in humans and other mammals. After infection, the cellular prion protein isoform PrP(C )is converted to the pathological PrP(SC )scrapie isoform. The continued conversion of...

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Bibliographic Details
Main Authors: Taheny, Michael J, Izkhakov, Nerik, Vostrov, Alexander A, Quitschke, Wolfgang W
Format: Artigo
Language:Inglês
Published: BioMed Central 2009
Subjects:
Short Report
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2751769/
https://ncbi.nlm.nih.gov/pubmed/19740434
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-0500-2-178
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