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Preparation and ocular pharmacokinetics of ganciclovir liposomes

Ophthalmic liposomes of ganciclovir (GCV) were prepared by the reverse phase evaporation method, and their ocular pharmacokinetics in albino rabbits were compared with those obtained after dosing with GCV solution. The in vitro transcorneal permeability of GCV liposomes was found to be 3.9-fold high...

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Detalhes bibliográficos
Main Authors: Shen, Yan, Tu, Jiasheng
Formato: Artigo
Idioma:Inglês
Publicado em: Springer-Verlag 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2751489/
https://ncbi.nlm.nih.gov/pubmed/18170984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/aapsj0903044
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