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Quantitative comparison of functional screening by measuring intracellular Ca(2+) with radioligand binding at recombinant human dopamine receptors

The purpose of this study was to test whether screening at dopamine receptors performed with a recently described functional assay for G-protein coupled receptors (GPCRs) provides data that correlate significantly with radioligand binding data in the literature, thus possibly allowing researchers to...

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Detalhes bibliográficos
Autor principal: Kassack, Matthias U.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer-Verlag 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2751320/
https://ncbi.nlm.nih.gov/pubmed/12646003
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/ps040431
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