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Quantitative comparison of functional screening by measuring intracellular Ca(2+) with radioligand binding at recombinant human dopamine receptors
The purpose of this study was to test whether screening at dopamine receptors performed with a recently described functional assay for G-protein coupled receptors (GPCRs) provides data that correlate significantly with radioligand binding data in the literature, thus possibly allowing researchers to...
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| Главный автор: | |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Springer-Verlag
2002
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2751320/ https://ncbi.nlm.nih.gov/pubmed/12646003 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/ps040431 |
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