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Influence of drug release properties of conventional solid dosage forms on the systemic exposure of highly soluble drugs
This study was designed to theoretically investigate the influence of drug release properties, characterized by the disintegration of a solid dosage form and dissolution of drug particles, on the systemic exposure of highly soluble drugs in immediate release products. An absorption model was develop...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
Springer-Verlag
2001
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2751019/ https://ncbi.nlm.nih.gov/pubmed/11741275 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/ps030324 |
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