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Pharmacokinetics of paclitaxel-containing liposomes in rats

In animal models, liposomal formulations of paclitaxel possess lower toxicity and equal antitumor efficacy compared with the clinical formulation, Taxol. The goal of this study was to determine the formulation dependence of paclitaxel pharmacokinetics in rats, in order to test the hypothesis that al...

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Autors principals: Fetterly, Gerald J., Straubinger, Robert M.
Format: Artigo
Idioma:Inglês
Publicat: Springer-Verlag 2003
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2750994/
https://ncbi.nlm.nih.gov/pubmed/15198520
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/ps050432
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