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Effect of pH on sublingual absorption of oxycodone hydrochloride

The purpose of this study was to develop a sublingual spray drug delivery formulation of oxycodone and evaluate the effect of formulation pH on sublingual absorption of oxycodone for acute pain management using rabbit as the animal model. Using a new, sensitive, and specific liquid chromatography/ma...

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Detalhes bibliográficos
Main Authors: Al-Ghananeem, Abeer M., Malkawi, Ahmad H., Crooks, Peter A.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer-Verlag 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2750730/
https://ncbi.nlm.nih.gov/pubmed/28290038
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/pt070123
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