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Determination of aqueous solubility by heating and equilibration: A technical note

A modified shake-flask solubility method, where the equilibration time was shortened through heating, was used to determine the solubility of 48 different drugs and pharmaceutical excipients in pure water at room temperature. The heating process accelerates dissolution of the solid compound and freq...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Loftsson, Thorsteinn, Hreinsdôttir, Dagný
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Springer-Verlag 2006
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2750711/
https://ncbi.nlm.nih.gov/pubmed/16584160
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/pt070104
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