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Once-daily sustained-release matrix tablets of nicorandil: Formulation and in vitro evaluation

The objective of the present study was to develop once-daily sustained-release matrix tablets of nicorandil, a novel potassium channel opener used in cardiovascular diseases. The tablets were prepared by the wet granulation method. Ethanolic solutions of ethylcellulose (EC), Eudragit RL-100, Eudragi...

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Detalhes bibliográficos
Main Authors: Reddy, K. Raghuram, Mutalik, Srinivas, Reddy, Srinivas
Formato: Artigo
Idioma:Inglês
Publicado em: Springer-Verlag 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2750654/
https://ncbi.nlm.nih.gov/pubmed/15198556
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/pt040461
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