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Effect of microenvironment pH of swellable and erodable buffered matrices on the release characteristics of diclofenac sodium

The aim of this work is to design pH-dependent swellable and erodable-buffered matrices and to study the effect of the microenvironment pH on the release pattern of diclofenac sodium. Buffered matrix tablets containing diclofenac sodium, physically mixed with hydrophilic polymer (hydroxypropyl methy...

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Detalhes bibliográficos
Main Authors: Al-Taani, Bashar M., Tashtoush, Bassam M.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer-Verlag 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2750636/
https://ncbi.nlm.nih.gov/pubmed/14621975
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/pt040343
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