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Design and in vitro and in vivo evaluation of mucoadhesive microcapsules of glipizide for oral controlled release: A technical note

Thus, large spherical microcapsules with a coat consisting of alginate and a mucoadhesive polymer (sodium CMC, methylcellulose, Carbopol, or HPMC) could be prepared by an orifice-ionic gelation process. The microcapsules exhibited good mucoadhesive properties in an in vitro test. Glipizide release f...

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Autors principals: Chowdary, K. P. R., Rao, Y. Srinivasa
Format: Artigo
Idioma:Inglês
Publicat: Springer-Verlag 2003
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2750632/
https://ncbi.nlm.nih.gov/pubmed/14621971
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/pt040339
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