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In vitro and in vivo evaluation of topical formulations of Spantide II

The purpose of this study was to develop and evaluate topical formulations of Spantide II, a neurokinin-1 receptor (NK-1R) antagonist, for the treatment of inflammatory skin disorders. Spantide II lotion and gel was formulated with and without n-methyl-2-pyrrolidone (NMP) as a penetration enhancer....

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Detalhes bibliográficos
Main Authors: Kikwai, Loice, Babu, R. Jayachandra, Prado, Renata, Kolot, Alexandra, Armstrong, Cheryl A., Ansel, John C., Singh, Mandip
Formato: Artigo
Idioma:Inglês
Publicado em: Springer-Verlag 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2750604/
https://ncbi.nlm.nih.gov/pubmed/16408858
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/pt060471
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