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Kinetics of paclitaxel 2′-N-methylpyridinium mesylate decomposition

This study was designed to examine the kinetics of decomposition of paclitaxel 2′-N-methylpyridinium mesylate (PNMM), a derivative of paclitaxel. Further, the potential for PNMM to act as a prodrug of paclitaxel was assessed in vitro. Stability studies of PNMM were conducted over a pH range of 4.0 t...

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Detalhes bibliográficos
Main Authors: Qasem, Jaber G., Bummer, Paul M., Digenis, George A.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer-Verlag 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2750599/
https://ncbi.nlm.nih.gov/pubmed/12916903
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/pt040221
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