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Low-temperature micronization of a peptide drug in fluid propellant: Case study cetrorelix
Aim of this study was to elaborate an efficient method for the micronization of the decapeptide cetrorelix (a GnRH-antagonist), in order to obtain a microsuspension as basis for other pharmaceutical preparations, such as e.g. inhalation aerosols. A modified pearl-mill coupled with a cryostat was use...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer-Verlag
2001
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2750577/ https://ncbi.nlm.nih.gov/pubmed/14727862 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/pt020312 |
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