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Development of a bladder instillation of the indoloquinone anticancer agent EO-9 using tert-butyl alcohol as lyophilization vehicle

The purpose of this research was to develop a stable bladder instillation of EO-9 for the treatment of superficial bladder cancer. First, stability and dissolution studies were performed. Subsequently, the freeze-drying process was optimized by determination of the freeze-drying characteristics of t...

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Bibliografske podrobnosti
Main Authors: van der Schoot, Sabien C., Nuijen, Bastiaan, Flesch, Frits M., Gore, Ashok, Mirejovsky, Dorla, Lenaz, Luigi, Beijnen, Jos H.
Format: Artigo
Jezik:Inglês
Izdano: Springer-Verlag 2007
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2750557/
https://ncbi.nlm.nih.gov/pubmed/17915828
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/pt0803061
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