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Transbuccal delivery of 5-Aza-2′-deoxycytidine: Effects of drug concentration, buffer solution, and bile salts on permeation

Delivery of 5-aza-2′-deoxycytidine (decitabine) across porcine buccal mucosa was evaluated as an alternative to the complex intravenous infusion regimen currently used to administer the drug. A reproducible high-performance liquid chromatography method was developed and optimized for the quantitativ...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Mahalingam, Ravichandran, Ravivarapu, Harish, Redkar, Sanjeev, Li, Xiaoling, Jasti, Bhaskara R.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Springer-Verlag 2007
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC2750551/
https://ncbi.nlm.nih.gov/pubmed/17915805
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/pt0803055
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