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Influence of long-term stability conditions on microbicidal nucleoside prodrug (WHI-07)-loaded gel-microemulsion

The objective of this study was to evaluate the long-term stability of the antiretroviral spermicide WHI-07 (5-bromo-6-methoxy-5,6-dihydro-3′-azidothymidine-5′-(p-bromophenyl)-methoxyalaninyl phosphate) in a polymer-based microemulsion. The recovery and stability of WHI-07 in gelmicroemulsion was ex...

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Detalhes bibliográficos
Main Authors: D’Cruz, Osmond J., Uckun, Fatih M.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer-Verlag 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2750515/
https://ncbi.nlm.nih.gov/pubmed/17025253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/pt070373
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