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Gastroretentive drug delivery system of carbamazepine: Formulation optimization using simplex lattice design: A technical note

An attempt was made to develop a gastroretentive drug delivery system of carbamazepine using HPMC, sodium bicarbonate, and EC as matrixing agent, gas-generating agent, and floating enhancer, respectively. A simplex lattice design was applied to investigate the combined effect of 3 formulation variab...

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Autors principals: Patel, Dasharath M., Patel, Natvarlal M., Pandya, Nitesh N., Jogani, Pranav D.
Format: Artigo
Idioma:Inglês
Publicat: Springer-Verlag 2007
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2750446/
https://ncbi.nlm.nih.gov/pubmed/18181543
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/pt0801011
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