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Stomach-specific drug delivery of 5-fluorouracil using floating alginate beads
A multiple-unit-type oral floating dosage form (FDF) of 5-fluorouracil (5-FU) was developed to prolong gastric residence time, target stomach cancer, and increase drug bioavailability. The floating bead formulations were prepared by dispersing 5-FU together with calcium carbonate into a mixture of s...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Springer-Verlag
2007
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2750363/ https://ncbi.nlm.nih.gov/pubmed/17625805 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/pt0802048 |
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