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Effect of oppositely charged polymer and dissolution medium on swelling, erosion, and drug release from chitosan matrices
The purpose of this research was to investigate the potential use of anionick-carrageenan and nonionic hydroxypropyl-methylcellulose (HPMC, K4) to improve the matrix integrity of directly compressed chitosan tablets containing naproxen sodium, an anionic drug. The influence of buffer pH and drug:pol...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer-Verlag
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2750359/ https://ncbi.nlm.nih.gov/pubmed/17622119 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/pt0802044 |
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