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Chitosan gels for the vaginal delivery of lactic acid: Relevance of formulation parameters to mucoadhesion and release mechanisms

The aim of this work was to assess the effect of formulation parameters of a mucoadhesive vaginal gel based on chitosan and lactic acid, and to highlight its release mechanisms. Two molecular weight chitosans were used to prepare gels with 2 lactic acid concentrations. Both chitosan molecular weight...

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Detalhes bibliográficos
Main Authors: Bonferoni, Maria Cristina, Giunchedi, Paolo, Scalia, Santo, Rossi, Silvia, Sandri, Giuseppina, Caramella, Carla
Formato: Artigo
Idioma:Inglês
Publicado em: Springer-Verlag 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2750341/
https://ncbi.nlm.nih.gov/pubmed/17285750
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/pt0704104
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