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Transdermal delivery of diclofenac sodium through rat skin from various formulations

The aim of this study was to evaluate and compare the in vitro and in vivo transdermal potential of w/o microemulsion (M) and gel (G) bases for diclofenac sodium (DS). The effect of dimethyl sulfoxide (DMSO) as a penetration enhancer was also examined when it was added to the M formulation. To study...

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Détails bibliographiques
Auteurs principaux: Özgüney, Işik Sarigüllü, Karasulu, Hatice Yeşim, Kantarci, Gülten, Sözer, Sumru, Güneri, Tamer, Ertan, Gökhan
Format: Artigo
Langue:Inglês
Publié: Springer-Verlag 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2750325/
https://ncbi.nlm.nih.gov/pubmed/16796357
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/pt070488
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