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Formulation and optimization of mouth dissolve tablets containing rofecoxib solid dispersion
The purpose of the present investigation was to increase the solubility and dissolution rate of rofecoxib by the preparation of its solid dispersion with polyvinyl pyrrolidone K30 (PVP K30) using solvent evaporation method. Drug-polymer interactions were investigated using differential scanning calo...
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| Autors principals: | , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Springer-Verlag
2006
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2750282/ https://ncbi.nlm.nih.gov/pubmed/16796372 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/pt070255 |
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