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Preparation and in vitro evaluation of polystyrene-coated diltiazem-resin complex by oil-in-water emulsion solvent evaporation method

The purpose of this study was to examine the suitability of polystyrene-coated (PS-coated) microcapsules of drug-resin complex for achieving prolonged release of diltiazem-HCl, a highly water-soluble drug, in simulated gastric and intestinal fluid. The drug was bound to Indion 254, a cation-exchange...

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Detalhes bibliográficos
Main Authors: Halder, Arindam, Sa, Biswanath
Formato: Artigo
Idioma:Inglês
Publicado em: Springer-Verlag 2006
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2750273/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/pt070246
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