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Effects of inducible nitric oxide synthase inhibition or norepinephrine on the neurovascular coupling in an endotoxic rat shock model

INTRODUCTION: The inducible nitric oxide synthase (iNOS) plays a crucial role in early sepsis-related microcirculatory dysfunction. Compared to a catecholamine therapy we tested effects of a specific iNOS-inhibitor (1400W) on the microcirculatory function in the brain. METHODS: Seventy SD-rats (280-...

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Bibliografiske detaljer
Main Authors: Rosengarten, Bernhard, Wolff, Stephanie, Klatt, Sabine, Schermuly, Ralf T
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2750197/
https://ncbi.nlm.nih.gov/pubmed/19709421
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/cc8020
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