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Targeting the ubiquitin proteasome pathway for the treatment of septic shock in patients
Endotoxic shock is a serious systemic inflammatory response to an external biological stressor. The responsiveness of NF-κB is built upon rapid protein modification and degradation involving the ubiquitin proteasome pathway. Using transgenic mice, we have obtained in vivo evidence that interference...
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| Hlavní autoři: | , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
BioMed Central
2009
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2750148/ https://ncbi.nlm.nih.gov/pubmed/19691815 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/cc7946 |
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