Allosteric β-propeller signalling in TolB and its manipulation by translocating colicins

The Tol system is a five-protein assembly parasitized by colicins and bacteriophages that helps stabilize the Gram-negative outer membrane (OM). We show that allosteric signalling through the six-bladed β-propeller protein TolB is central to Tol function in Escherichia coli and that this is subverte...

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Main Authors: Bonsor, Daniel A, Hecht, Oliver, Vankemmelbeke, Mireille, Sharma, Amit, Krachler, Anne Marie, Housden, Nicholas G, Lilly, Katie J, James, Richard, Moore, Geoffrey R, Kleanthous, Colin
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2750012/
https://ncbi.nlm.nih.gov/pubmed/19696740
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2009.224
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