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Glucocorticoids with different chemical structures but similar glucocorticoid receptor potency regulate subsets of common and unique genes in human trabecular meshwork cells

BACKGROUND: In addition to their well-documented ocular therapeutic effects, glucocorticoids (GCs) can cause sight-threatening side-effects including ocular hypertension presumably via morphological and biochemical changes in trabecular meshwork (TM) cells. In the present study, we directly compared...

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Autors principals: Nehmé, Alissar, Lobenhofer, Edward K, Stamer, W Daniel, Edelman, Jeffrey L
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2749862/
https://ncbi.nlm.nih.gov/pubmed/19744340
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1755-8794-2-58
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