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Force and Premature Binding of ADP Can Regulate the Processivity of Individual Eg5 Dimers
Using a high-resolution optical trapping instrument, we directly observed the processive motions of individual Eg5 dimers over a range of external loads and ATP, ADP, and phosphate concentrations. To constrain possible models for dissociation from the microtubule, we measured Eg5 run lengths and als...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Biophysical Society
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2749793/ https://ncbi.nlm.nih.gov/pubmed/19751672 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2009.07.013 |
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