Diffusion of Large Molecules into Assembling Nuclei Revealed Using an Optical Highlighting Technique

The nuclear envelope (NE) defines the nuclear compartment, and nuclear pore complexes (NPCs) on the NE form aqueous passages through which small water-soluble molecules can passively diffuse. It is well known that proteins smaller than 50 kDa can diffuse though NPCs, whereas proteins larger than 60...

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Bibliographic Details
Main Authors: Shimozono, Satoshi, Tsutsui, Hidekazu, Miyawaki, Atsushi
Format: Artigo
Language:Inglês
Published: The Biophysical Society 2009
Subjects:
Cellular Biophysics and Electrophysiology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2749756/
https://ncbi.nlm.nih.gov/pubmed/19720016
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2009.06.024
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