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Estimation of the effects of smoking and DNA repair capacity on coefficients of a carcinogenesis model for lung cancer

Numerous prospective and retrospective studies have clearly demonstrated a dose-related increased lung cancer risk associated with cigarette smoking, with evidence also for a genetic component to risk. In this study, using the two-stage clonal expansion stochastic model framework, for the first time...

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Detalhes bibliográficos
Main Authors: Deng, Li, Kimmel, Marek, Foy, Millennia, Spitz, Margaret, Wei, Qingyi, Gorlova, Olga
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2749693/
https://ncbi.nlm.nih.gov/pubmed/19123470
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.24149
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